DDK (Dbf4-dependent kinase) catalytic subunit; required for origin firing and replication fork progression in mitotic S phase through phosphorylation of Mcm2-7p complexes and Cdc45p; kinase activity correlates with cyclical DBF4 expression; required for pre-meiotic DNA replication, meiotic DSB formation, recruitment of monopolin complex to kinetochores during meiosis I, regulation of meiosis-specific Ndt80p; mutation complemented by human CDC7 and DBF4 co-expression [Source:SGD;Acc:S000002175]
Chromosome IV: 424,209-425,732 forward strand.
This transcript has 1 exon, is annotated with 12 domains and features, is associated with 26 variant alleles and maps to 29 oligo probes.
This transcript is a product of gene YDL017W Show transcript tableHide transcript table
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
CDC7 | YDL017W_mRNA | 1524 | 507aa | YDL017W | Protein coding | P06243 | - | Ensembl Canonical, |