Catalytic subunit of the histone acetyltransferase complex (NuA4); acetylates four conserved internal lysines of histone H4 N-terminal tail and can acetylate histone H2A; master regulator of cellular acetylation balance; required for cell cycle progression and transcriptional silencing at the rDNA locus and regulation of autophagy; human ortholog TIP60/KAT5 is implicated in cancer and other diseases, functionally complements lethality of the esa1 null mutation [Source:SGD;Acc:S000005770]

Chromosome XV: 792,531-793,868 forward strand.

This transcript has 1 exon, is annotated with 26 domains and features, is associated with 21 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YOR244W Show transcript tableHide transcript table