E3 ubiquitin ligase of the hect-domain class; has a role in mRNA export from the nucleus and may regulate transcriptional coactivators; involved in degradation of excess histones; interacts with Dia2p and is required for Dia2p degradation; required to target Cdc6p for ubiquitin-mediated destruction during G1 phase [Source:SGD;Acc:S000002865]

Chromosome IV: 1,369,790-1,379,596 forward strand.

This transcript has 1 exon, is annotated with 30 domains and features, is associated with 97 variant alleles and maps to 119 oligo probes.

This transcript is a product of gene YDR457W Show transcript tableHide transcript table