NAD(+)-dependent protein deacetylase; deacetylation targets are primarily mitochondrial proteins; involved along with Hst3p in silencing at telomeres, cell cycle progression, radiation resistance, genomic stability and short-chain fatty acid metabolism; accumulates in mitochondria in response to biotin starvation and may link biotin metabolism with energy homeostasis; member of the Sir2 family and may be the functional equivalent of human SIRT3 [Source:SGD;Acc:S000002599]

Chromosome IV: 842,337-843,449 forward strand.

This transcript has 1 exon, is annotated with 11 domains and features, is associated with 38 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YDR191W Show transcript tableHide transcript table