Catalytic subunit of ADA and SAGA histone acetyltransferase complexes; modifies N-terminal lysines on histones H2B and H3; acetylates Rsc4p, a subunit of the RSC chromatin-remodeling complex, altering replication stress tolerance; relocalizes to the cytosol in response to hypoxia; mutant displays reduced transcription elongation in the G-less-based run-on (GLRO) assay; greater involvement in repression of RNAPII-dependent transcription than in activation [Source:SGD;Acc:S000003484]

Chromosome VII: 996,869-998,188 forward strand.

This transcript has 1 exon, is annotated with 19 domains and features, is associated with 23 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YGR252W Show transcript tableHide transcript table