Catalytic subunit of ADA and SAGA histone acetyltransferase complexes; modifies N-terminal lysines on histones H2B and H3; acetylates Rsc4p, a subunit of the RSC chromatin-remodeling complex, altering replication stress tolerance; relocalizes to the cytosol in response to hypoxia; mutant displays reduced transcription elongation in the G-less-based run-on (GLRO) assay; greater involvement in repression of RNAPII-dependent transcription than in activation [Source:SGD;Acc:S000003484]

AAS104, ADA4, KAT2, SWI9

Chromosome VII: 996,869-998,188 forward strand.

R64-1-1:BK006941.2

This gene has 1 transcript (splice variant), 419 orthologues and 2 paralogues.

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