Saccharomyces cerevisiae (R64-1-1)
Description

Exosome core complex catalytic subunit; has both endonuclease and 3'-5' exonuclease activity; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; role in degradation of tRNAs; similar to E. coli RNase R and to human DIS3, which partially complements dis3-81 heat sensitivity; mutations in Dis3p analogous to human mutations implicated in multiple myeloma impair exosome function; protein abundance increases under to DNA replication stress [Source:SGD;Acc:S000005381]

Location
About this transcript

This transcript has 1 exon, is annotated with 24 domains and features, is associated with 61 variant alleles and maps to 29 oligo probes.

Gene

This transcript is a product of gene YOL021C Show transcript tableHide transcript table

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
NovelYOL021C_mRNA30061001aaYOL021C
 
Protein coding
Q08162 NM_001183275.1
NP_014621.1
Statistics

Exons: 1, Coding exons: 1, Transcript length: 3,006 bps, Translation length: 1,001 residues

Uniprot

This transcript corresponds to the following Uniprot identifiers: Q08162

Version

YOL021C_mRNA.

Type

Protein coding

Annotation Method

Genes annotated by SGD

Transcript-based displays