Saccharomyces cerevisiae (R64-1-1)
Description

Topoisomerase II; relieves torsional strain in DNA by cleaving and re-sealing phosphodiester backbone of both positively and negatively supercoiled DNA; cleaves complementary strands; localizes to axial cores in meiosis; required for replication slow zone (RSZ) breakage following Mec1p inactivation; human homolog TOP2A implicated in cancers, and can complement yeast null mutant [Source:SGD;Acc:S000005032]

Location
About this transcript

This transcript has 1 exon, is annotated with 61 domains and features, is associated with 49 variant alleles and maps to 29 oligo probes.

Gene

This transcript is a product of gene YNL088W Show transcript tableHide transcript table

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
TOP2YNL088W_mRNA42871428aaYNL088W
 
Protein coding
P06786 NM_001182926.3
NP_014311.3
Statistics

Exons: 1, Coding exons: 1, Transcript length: 4,287 bps, Translation length: 1,428 residues

Uniprot

This transcript corresponds to the following Uniprot identifiers: P06786

Version

YNL088W_mRNA

Type

Protein coding

Annotation Method

Annotation imported from SGD

Transcript-based displays