rRNA m5C methyltransferase; methylates cytosine at position 2870 of 25S rRNA; has an essential function independent of rRNA methylation; contains seven beta-strand methyltransferase motif; essential for processing and maturation of 27S pre-rRNA and large ribosomal subunit biogenesis; localized to the nucleolus; constituent of 66S pre-ribosomal particles; rRNA methylation defect and lethality are functionally complemented by human NOP2, a gene upregulated in cancer [Source:SGD;Acc:S000005005]

Chromosome XIV: 510,540-512,396 forward strand.

This transcript has 1 exon, is annotated with 34 domains and features and is associated with 42 variant alleles.

This transcript is a product of gene YNL061W Show transcript tableHide transcript table