NADH:ubiquinone oxidoreductase; transfers electrons from NADH to ubiquinone in respiratory chain but does not pump protons, in contrast to higher eukaryotic multisubunit respiratory complex I; upon apoptotic stress, is activated in mitochondria by N-terminal cleavage, then translocates to cytoplasm to induce apoptosis; homolog of human AIFM2; yeast NDI1 complements several phenotypes of human cell line with mutated MT-ND4, implicated in Leber hereditary optic neuropathy [Source:SGD;Acc:S000004589]

Chromosome XIII: 28,266-29,807 reverse strand.

This transcript has 1 exon, is annotated with 11 domains and features, is associated with 30 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YML120C Show transcript tableHide transcript table