Guanine nucleotide exchange factor (GEF) and ubiquitin receptor; involved in vesicle-mediated vacuolar transport, including Golgi-endosome trafficking and sorting through the multivesicular body (MVB); stimulates the intrinsic guanine nucleotide exchange activity of Rab family members (Vps21p/Ypt52p/Ypt53p); partially redundant with GEF MUK1; required for localization of the CORVET complex to endosomes; similar to mammalian ras inhibitors; contains a Ub-interacting CUE domain [Source:SGD;Acc:S000004563]

Chromosome XIII: 78,335-79,690 reverse strand.

This transcript has 1 exon, is annotated with 22 domains and features and is associated with 47 variant alleles.

This transcript is a product of gene YML097C Show transcript tableHide transcript table