Saccharomyces cerevisiae (R64-1-1)
Description

HMG-CoA reductase; converts HMG-CoA to mevalonate, a rate-limiting step in sterol biosynthesis; one of two isozymes; overproduction induces assembly of peripheral ER membrane arrays and short nuclear-associated membrane stacks; forms foci at nuclear periphery upon DNA replication stress; HMG2 has a paralog, HMG1, that arose from the whole genome duplication; human homolog HMGCR can complement yeast hmg2 mutant [Source:SGD;Acc:S000004442]

Location
About this transcript

This transcript has 1 exon, is annotated with 36 domains and features, is associated with 52 variant alleles and maps to 29 oligo probes.

Gene

This transcript is a product of gene YLR450W Show transcript tableHide transcript table

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
HMG2YLR450W_mRNA31381045aaYLR450W
 
Protein coding
P12684 -Ensembl Canonical
Statistics

Exons: 1, Coding exons: 1, Transcript length: 3,138 bps, Translation length: 1,045 residues

Uniprot

This transcript corresponds to the following Uniprot identifiers: P12684

Version

YLR450W_mRNA

Type

Protein coding

Annotation Method

Annotation imported from SGD