Peptidyl-prolyl cis-trans isomerase (PPIase); nuclear proline isomerase; affects expression of multiple genes via its role in nucleosome assembly; catalyzes isomerization of proline residues in histones H3 and H4, which affects lysine methylation of those histones; PPIase domain acts as a transcriptional repressor when tethered to DNA by lexA, and repressor activity is dependent on PPIase activity; contains a nucleoplasmin-like fold and can form pentamers [Source:SGD;Acc:S000004441]
Chromosome XII: 1,030,834-1,032,012 forward strand.
This transcript has 1 exon, is annotated with 18 domains and features, is associated with 23 variant alleles and maps to 29 oligo probes.
This transcript is a product of gene YLR449W Show transcript tableHide transcript table