Component of the Paf1p complex; binds to and modulates the activity of RNA polymerases I and II; required for expression of certain genes, modification of some histones, and telomere maintenance; involved in transcription elongation as demonstrated by the G-less-based run-on (GLRO) assay; protein abundance increases in response to DNA replication stress; human homolog, parafibromin, is a tumour suppressor linked to breast, renal and gastric cancers [Source:SGD;Acc:S000004410]

Chromosome XII: 956,914-958,095 reverse strand.

This transcript has 1 exon, is annotated with 6 domains and features, is associated with 30 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YLR418C Show transcript tableHide transcript table