mRNA-binding protein expressed during iron starvation; binds to a sequence element in the 3'-untranslated regions of specific mRNAs to mediate their degradation; involved in iron homeostasis; protein increases in abundance and relative distribution to the nucleus increases upon DNA replication stress; TIS11 has a paralog, CTH1, that arose from the whole genome duplication [Source:SGD;Acc:S000004126]
Chromosome XII: 415,801-416,658 reverse strand.
This transcript has 1 exon, is annotated with 15 domains and features, is associated with 22 variant alleles and maps to 29 oligo probes.
This transcript is a product of gene YLR136C Show transcript tableHide transcript table
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
TIS11 | YLR136C_mRNA | 858 | 285aa | YLR136C | Protein coding | P47977 | - | Ensembl Canonical, |