Saccharomyces cerevisiae (R64-1-1)
Description

DNA replication initiation factor; recruited to MCM pre-RC complexes at replication origins; promotes release of MCM from Mcm10p, recruits elongation machinery; binds tightly to ssDNA, which disrupts interaction with the MCM helicase and stalls it during replication stress; mutants in human homolog may cause velocardiofacial and DiGeorge syndromes [Source:SGD;Acc:S000004093]

Location
About this transcript

This transcript has 1 exon, is annotated with 8 domains and features, is associated with 47 variant alleles and maps to 29 oligo probes.

Gene

This transcript is a product of gene YLR103C Show transcript tableHide transcript table

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
CDC45YLR103C_mRNA1953650aaYLR103C
 
Protein coding
Q08032 NM_001181990.1
NP_013204.1
Statistics

Exons: 1, Coding exons: 1, Transcript length: 1,953 bps, Translation length: 650 residues

Uniprot

This transcript corresponds to the following Uniprot identifiers: Q08032

Version

YLR103C_mRNA

Type

Protein coding

Annotation Method

Annotation imported from SGD

Transcript-based displays