Saccharomyces cerevisiae (R64-1-1)
Description

RNA lariat debranching enzyme; catalyzes debranching of lariat introns formed during pre-mRNA splicing; required for efficient Ty1 transposition; knockdown of human homolog Dbr1 rescues toxicity of RNA-binding proteins TDP-43 and FUS which are implicated in amyotrophic lateral sclerosis (ALS), suggests potential therapeutic target for ALS and related TDP-43 proteinopathies; human homolog DBR1 can complement yeast dbr1 null mutant [Source:SGD;Acc:S000001632]

Location
About this transcript

This transcript has 1 exon, is annotated with 11 domains and features, is associated with 32 variant alleles and maps to 29 oligo probes.

Gene

This transcript is a product of gene YKL149C Show transcript tableHide transcript table

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
DBR1YKL149C_mRNA1218405aaYKL149C
 
Protein coding
P24309 -Ensembl Canonical
Statistics

Exons: 1, Coding exons: 1, Transcript length: 1,218 bps, Translation length: 405 residues

Uniprot

This transcript corresponds to the following Uniprot identifiers: P24309

Version

YKL149C_mRNA

Type

Protein coding

Annotation Method

Annotation imported from SGD