Endosomal protein involved in turnover of plasma membrane proteins; member of the DUP380 subfamily of conserved, often subtelomeric COS genes; required for the multivesicular vesicle body sorting pathway that internalizes plasma membrane proteins for degradation; Cos proteins provide ubiquitin in trans for nonubiquitinated cargo proteins [Source:SGD;Acc:S000003527]
Chromosome VII: 1,081,584-1,082,729 reverse strand.
This transcript has 1 exon, is annotated with 6 domains and features, is associated with 203 variant alleles and maps to 74 oligo probes.
This transcript is a product of gene YGR295C Show transcript tableHide transcript table