Saccharomyces cerevisiae (R64-1-1)
Description

Negative regulator of actin nucleation-promoting factor activity; interacts with Las17p, a homolog of human Wiskott-Aldrich Syndrome protein (WASP), via an N-terminal SH3 domain, and along with PIN3 cooperatively inhibits the nucleation of actin filaments; overexpression blocks receptor-mediated endocytosis; protein increases in abundance and forms nuclear foci in response to DNA replication stress; LSB1 has a paralog, PIN3, that arose from the whole genome duplication [Source:SGD;Acc:S000003368]

Location
About this transcript

This transcript has 1 exon, is annotated with 25 domains and features, is associated with 18 variant alleles and maps to 46 oligo probes.

Gene

This transcript is a product of gene YGR136W Show transcript tableHide transcript table

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
NovelYGR136W_mRNA726241aaYGR136W
 
Protein coding
P53281 NM_001181265.1
NP_011652.1
Statistics

Exons: 1, Coding exons: 1, Transcript length: 726 bps, Translation length: 241 residues

Uniprot

This transcript corresponds to the following Uniprot identifiers: P53281

Version

YGR136W_mRNA.

Type

Protein coding

Annotation Method

Genes annotated by SGD

Transcript-based displays