Hexokinase isoenzyme 2; phosphorylates glucose in cytosol; predominant hexokinase during growth on glucose; represses expression of HXK1, GLK1, induces expression of its own gene; antiapoptotic; phosphorylation/dephosphorylation at Ser14 by kinase Snf1p, phosphatase Glc7p-Reg1p regulates nucleocytoplasmic shuttling of Hxk2p; functions downstream of Sit4p in control of cell cycle, mitochondrial function, oxidative stress resistance, chronological lifespan; has paralog HXK1 [Source:SGD;Acc:S000003222]
Chromosome VII: 23,935-25,395 forward strand.
This transcript has 1 exon, is annotated with 27 domains and features, is associated with 12 variant alleles and maps to 29 oligo probes.
This transcript is a product of gene YGL253W Show transcript tableHide transcript table
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
HXK2 | YGL253W_mRNA | 1461 | 486aa | YGL253W | Protein coding | P04807 | - | Ensembl Canonical, |