Phosphoinositide binding protein; required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; binds both phosphatidylinositol (3,5)-bisphosphate and phosphatidylinositol 3-phosphate; WD-40 repeat protein; relocalizes from vacuole to cytoplasm upon DNA replication stress; has 4 mammalian homologs WIPI1, WIPI2, WIPI3 and WIPI4/WDR45; mutations in human WDR45 cause static encephalopathy of childhood with neurodegeneration in adulthood [Source:SGD;Acc:S000001917]

Chromosome VI: 194,812-196,314 forward strand.

This transcript has 1 exon, is annotated with 12 domains and features, is associated with 27 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YFR021W Show transcript tableHide transcript table