Saccharomyces cerevisiae (R64-1-1)
Description

NEDD4 family E3 ubiquitin ligase; regulates processes including: MVB sorting, the heat shock response, transcription, endocytosis and ribosome stability; ubiquitinates Sec23p, Sna3p, Ste4p, Nfi1p, Rpo21p and Sem1p; autoubiquitinates; deubiquitinated by Ubp2p; regulated by SUMO ligase Siz1p, in turn regulates Siz1p SUMO ligase activity; required for efficient Golgi-to-ER trafficking in COPI mutants; mutant tolerates aneuploidy; human homolog implicated in Liddle syndrome [Source:SGD;Acc:S000000927]

Location
About this transcript

This transcript has 1 exon, is annotated with 47 domains and features, is associated with 20 variant alleles and maps to 29 oligo probes.

Gene

This transcript is a product of gene YER125W Show transcript tableHide transcript table

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
RSP5YER125W_mRNA2430809aaYER125W
 
Protein coding
P39940 -Ensembl Canonical
Statistics

Exons: 1, Coding exons: 1, Transcript length: 2,430 bps, Translation length: 809 residues

Uniprot

This transcript corresponds to the following Uniprot identifiers: P39940

Version

YER125W_mRNA

Type

Protein coding

Annotation Method

Annotation imported from SGD