RNA-binding protein; promotes elongation, regulates termination, and carries poly(A) mRNA from nucleus to cytoplasm; represses translation initiation by binding eIF4G; required for pre-mRNA splicing; interacts with E3 ubiquitin ligase Bre1p, linking histone ubiquitination to mRNA processing; may have role in telomere maintenance; dissociation from mRNAs promoted by Mtr10p; phosphorylated by Sky1p in cytoplasm; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000002840]

Chromosome IV: 1,328,783-1,330,027 forward strand.

This transcript has 1 exon, is annotated with 24 domains and features, is associated with 17 variant alleles and maps to 47 oligo probes.

This transcript is a product of gene YDR432W Show transcript tableHide transcript table