Subunit of DNA pol epsilon and of ISW2 chromatin accessibility complex; involved in both chromosomal DNA replication and inheritance of telomeric silencing; stabilizes the interaction of Pol epsilon with primer-template DNA, positively affecting the processivity of the polymerase and exonuclease activities of Pol epsilon; interacts with extranucleosomal DNA and acts as anchor point for ISW2 complex that retains its position on DNA during nucleosome mobilization [Source:SGD;Acc:S000002528]

Chromosome IV: 693,585-694,175 forward strand.

This transcript has 1 exon, is annotated with 8 domains and features, is associated with 16 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YDR121W Show transcript tableHide transcript table