Catalytic subunit of the COP9 signalosome (CSN) complex; acts as an isopeptidase in cleaving the ubiquitin-like protein Nedd8 from SCF ubiquitin ligases; metalloendopeptidase involved in the adaptation to pheromone signaling; involved in modulation of genes controlling amino acid and lipid metabolism, and ergosterol biosynthesis [Source:SGD;Acc:S000002375]

Chromosome IV: 68,997-70,319 reverse strand.

This transcript has 1 exon, is annotated with 9 domains and features, is associated with 54 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YDL216C Show transcript tableHide transcript table