2'-O-ribose methyltransferase; methylates the 2'-O-ribose of tRNA-Phe, tRNA-Trp, and tRNA-Leu at positions C32 and N34 of tRNA anticodon loop; crucial biological role likely modification of tRNA-Phe; interacts with Trm732p and Rtt10p in 2'-O-methylation of C32 and N34 substrate tRNAs, respectively; yeast null mutant can be functionally complemented by human FTSJ1, mutations in which have been implicated in nonsyndromic X-linked intellectual disability (NSXLID) [Source:SGD;Acc:S000000265]
Chromosome II: 364,787-365,719 reverse strand.
This transcript has 1 exon, is annotated with 8 domains and features, is associated with 29 variant alleles and maps to 29 oligo probes.
This transcript is a product of gene YBR061C Show transcript tableHide transcript table