Heme-dependent repressor of hypoxic genes; mediates aerobic transcriptional repression of hypoxia induced genes such as COX5b and CYC7; repressor function regulated through decreased promoter occupancy in response to oxidative stress; contains an HMG domain that is responsible for DNA bending activity; involved in the hyperosmotic stress resistance [Source:SGD;Acc:S000006269]
Chromosome XVI: 679,693-680,799 forward strand.
This transcript has 1 exon, is annotated with 21 domains and features and is associated with 48 variant alleles.
This transcript is a product of gene YPR065W Show transcript tableHide transcript table
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
ROX1 | YPR065W_mRNA | 1107 | 368aa | YPR065W | Protein coding | P25042 | - | Ensembl Canonical, |