ATP-dependent 5' to 3' RNA/DNA and DNA helicase; subunit of the exosome-associated Nrd1p complex that mediates 3' end formation of snRNAs, snoRNAs, CUTs and some mRNAs; helicase-independent role in transcription-coupled repair; coordinates replication with transcription, associating with moving forks and preventing errors that occur when forks encounter transcribed regions; homolog of Senataxin, implicated in Ataxia-Oculomotor Apraxia 2 and a dominant form of juvenile ALS [Source:SGD;Acc:S000004422]
Chromosome XII: 993,434-1,000,129 forward strand.
This transcript has 1 exon, is annotated with 35 domains and features, is associated with 93 variant alleles and maps to 92 oligo probes.
This transcript is a product of gene YLR430W Show transcript tableHide transcript table