DNA replication initiation factor; recruited to MCM pre-RC complexes at replication origins; promotes release of MCM from Mcm10p, recruits elongation machinery; binds tightly to ssDNA, which disrupts interaction with the MCM helicase and stalls it during replication stress; mutants in human homolog may cause velocardiofacial and DiGeorge syndromes [Source:SGD;Acc:S000004093]

Chromosome XII: 343,989-345,941 reverse strand.

This transcript has 1 exon, is annotated with 12 domains and features and is associated with 47 variant alleles.

This transcript is a product of gene YLR103C Show transcript tableHide transcript table