Essential protein with distinct roles in two nuclear pore subcomplexes; catalyzes its own proteolytic cleavage in vivo to generate a C-terminal fragment that is a structural component of the Nup84p subcomplex (with roles in NPC biogenesis and localization of genes to the nuclear periphery), and an N-terminal fragment that is one of several FG-nucleoporins within the NPC central core directly responsible for nucleocytoplasmic transport; homologous to human NUP98 [Source:SGD;Acc:S000003060]

Chromosome VII: 337,906-341,859 forward strand.

This transcript has 1 exon, is annotated with 21 domains and features, is associated with 78 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YGL092W Show transcript tableHide transcript table