Essential protein with distinct roles in two nuclear pore subcomplexes; catalyzes its own proteolytic cleavage in vivo to generate a C-terminal fragment that is a structural component of the Nup84p subcomplex (with roles in NPC biogenesis and localization of genes to the nuclear periphery), and an N-terminal fragment that is one of several FG-nucleoporins within the NPC central core directly responsible for nucleocytoplasmic transport; homologous to human NUP98 [Source:SGD;Acc:S000003060]
Chromosome VII: 337,906-341,859 forward strand.
This transcript has 1 exon, is annotated with 27 domains and features and is associated with 78 variant alleles.
This transcript is a product of gene YGL092W Show transcript tableHide transcript table
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
NUP145 | YGL092W_mRNA | 3954 | 1317aa | YGL092W | Protein coding | P49687 | - | Ensembl Canonical, |