Major isoform of large subunit of ribonucleotide-diphosphate reductase; the RNR complex catalyzes rate-limiting step in dNTP synthesis, regulated by DNA replication and DNA damage checkpoint pathways via localization of small subunits; relative distribution to the nucleus increases upon DNA replication stress; RNR1 has a paralog, RNR3, that arose from the whole genome duplication [Source:SGD;Acc:S000000872]

Chromosome V: 298,950-301,616 forward strand.

This transcript has 1 exon, is annotated with 25 domains and features and is associated with 28 variant alleles.

This transcript is a product of gene YER070W Show transcript tableHide transcript table