Major isoform of large subunit of ribonucleotide-diphosphate reductase; the RNR complex catalyzes rate-limiting step in dNTP synthesis, regulated by DNA replication and DNA damage checkpoint pathways via localization of small subunits; relative distribution to the nucleus increases upon DNA replication stress; RNR1 has a paralog, RNR3, that arose from the whole genome duplication [Source:SGD;Acc:S000000872]

CRT7, RIR1, SDS12

Chromosome V: 298,950-301,616 forward strand.

R64-1-1:BK006939.2

This gene has 1 transcript (splice variant), 415 orthologues and 1 paralogue.

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