DDK (Dbf4-dependent kinase) catalytic subunit; required for origin firing and replication fork progression in mitotic S phase through phosphorylation of Mcm2-7p complexes and Cdc45p; kinase activity correlates with cyclical DBF4 expression; required for pre-meiotic DNA replication, meiotic DSB formation, recruitment of monopolin complex to kinetochores during meiosis I, regulation of meiosis-specific Ndt80p; mutation complemented by human CDC7 and DBF4 co-expression [Source:SGD;Acc:S000002175]

Chromosome IV: 424,209-425,732 forward strand.

This transcript has 1 exon, is annotated with 13 domains and features and is associated with 26 variant alleles.

This transcript is a product of gene YDL017W Show transcript tableHide transcript table