Protein disulfide isomerase; multifunctional oxidoreductase of the ER lumen, essential for disulfide bond formation in secretory and cell-surface proteins, processing of non-native disulfide bonds; Ero1p activator; complexes with exomannosidase, Mnl1p to facilitate the recognition of misfolded glycoproteins and the trimming of glycan Man8GlcNAc2 to Man7GlcNAc2 on substrates, thereby accelerating ERAD; PDI1 has a paralog, EUG1, that arose from the whole genome duplication [Source:SGD;Acc:S000000548]

Chromosome III: 48,653-50,221 reverse strand.

This transcript has 1 exon, is annotated with 33 domains and features, is associated with 38 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YCL043C Show transcript tableHide transcript table