ATPase subunit of imitation-switch (ISWI) class chromatin remodelers; with Ioc3p forms Isw1a complex involved in repression of transcription initiation; with Ioc2p and Ioc4p forms Isw1b complex involved in regulation of transcription elongation; Isw1b recruited to ORFs by H3K36 methylation and acts with Chd1p to prevent trans-histone exchange over coding regions; Isw1p import into nucleus depends on C-terminal bipartite nuclear targeting signal KRIR X19 KKAK [Source:SGD;Acc:S000000449]
Chromosome II: 708,150-711,539 reverse strand.
This transcript has 1 exon, is annotated with 39 domains and features, is associated with 45 variant alleles and maps to 29 oligo probes.
This transcript is a product of gene YBR245C Show transcript tableHide transcript table