Ubiquitin-conjugating enzyme (E2); key E2 partner with Ubc1p for the anaphase-promoting complex (APC); mediates degradation of abnormal or excess proteins, including calmodulin and histone H3; regulates levels of DNA Polymerase-{alpha} to promote efficient and accurate DNA replication; interacts with many SCF ubiquitin protein ligases; component of the cellular stress response; UBC4 has a paralog, UBC5, that arose from the whole genome duplication [Source:SGD;Acc:S000000286]

Chromosome II: 406,628-407,169 reverse strand.

This transcript has 2 exons, is annotated with 17 domains and features, is associated with 13 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YBR082C Show transcript tableHide transcript table