Ubiquitin-conjugating enzyme (E2); key E2 partner with Ubc1p for the anaphase-promoting complex (APC); mediates degradation of abnormal or excess proteins, including calmodulin and histone H3; regulates levels of DNA Polymerase-{alpha} to promote efficient and accurate DNA replication; interacts with many SCF ubiquitin protein ligases; component of the cellular stress response; UBC4 has a paralog, UBC5, that arose from the whole genome duplication [Source:SGD;Acc:S000000286]
Chromosome II: 406,628-407,169 reverse strand.
R64-1-1:BK006936.2
This gene has 1 transcript (splice variant), 183 orthologues and 1 paralogue.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
UBC4 | YBR082C_mRNA | 447 | 148aa | YBR082C | Protein coding | P15731 | - | Ensembl Canonical, |