Vacuolar membrane protein; transits through the biosynthetic vacuolar protein sorting pathway, involved in sphingolipid metabolism; cells lacking Ncr1p exhibit high levels of long chain bases (LCB), similar to the accumulation of high amounts of lipids observed in patients with Neimann-Pick C, a disease caused by loss-of-function mutations in NPC1, the functional ortholog of Ncr1p [Source:SGD;Acc:S000005927]

Chromosome XVI: 544,631-548,143 forward strand.

This transcript has 1 exon, is annotated with 33 domains and features, is associated with 65 variant alleles and maps to 57 oligo probes.

This transcript is a product of gene YPL006W Show transcript tableHide transcript table