Saccharomyces cerevisiae (R64-1-1)
Description

Vacuolar membrane protein; transits through the biosynthetic vacuolar protein sorting pathway, involved in sphingolipid metabolism; cells lacking Ncr1p exhibit high levels of long chain bases (LCB), similar to the accumulation of high amounts of lipids observed in patients with Neimann-Pick C, a disease caused by loss-of-function mutations in NPC1, the functional ortholog of Ncr1p [Source:SGD;Acc:S000005927]

Location

Chromosome XVI: 544,631-548,143 forward strand.

R64-1-1:BK006949.2

About this gene

This gene has 1 transcript (splice variant), 203 orthologues and is a member of 2 Ensembl protein families.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
NCR1YPL006W_mRNA35131170aaYPL006W
 
Protein coding
Q12200 NM_001183820.1
NP_015319.1

Gene-based displays