Subunit of cohesin loading factor (Scc2p-Scc4p); a complex required for loading of cohesin complexes onto chromosomes; involved in establishing sister chromatid cohesion during DSB repair via histone H2AX; promotes gene expression program that supports translational fidelity; evolutionarily-conserved adherin; relocalizes to cytosol in response to hypoxia; human disorder Cornelia de Lange syndrome is caused by mutations in NIPBL, the human ortholog of SCC2 [Source:SGD;Acc:S000002588]

Chromosome IV: 821,295-825,776 forward strand.

This transcript has 1 exon, is annotated with 10 domains and features, is associated with 55 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YDR180W Show transcript tableHide transcript table