Guanine nucleotide exchange factor for Gpa1p; amplifies G protein signaling; functions as a chaperone under ATP-depleted oxidative stress conditions; subunit of GET complex, involved in ATP dependent Golgi to ER trafficking and insertion of tail-anchored (TA) proteins into ER membrane under non-stress conditions; binds as dimer to transmembrane domain (TMD) cargo, shielding TMDs from aqueous solvent; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000002258]
Chromosome IV: 282,112-283,176 reverse strand.
This transcript has 1 exon, is annotated with 18 domains and features, is associated with 22 variant alleles and maps to 29 oligo probes.
This transcript is a product of gene YDL100C Show transcript tableHide transcript table