Ski complex component and TPR protein; mediates 3'-5' RNA degradation by the cytoplasmic exosome; null mutants have superkiller phenotype of increased viral dsRNAs and are synthetic lethal with mutations in 5'-3' mRNA decay; mutations in the human ortholog, TTC37, causes Syndromic diarrhea/Trichohepatoenteric (SD/THE) syndrome [Source:SGD;Acc:S000006393]
SKI5
Chromosome XVI: 912,664-916,962 forward strand.
R64-1-1:BK006949.2
This gene has 1 transcript (splice variant) and 369 orthologues.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
SKI3 | YPR189W_mRNA | 4299 | 1432aa | YPR189W | Protein coding | P17883 | - | Ensembl Canonical, |