Subunit of heterodimeric nuclear SUMO activating enzyme E1 with Uba2p; activates Smt3p (SUMO) before its conjugation to proteins (sumoylation), which may play a role in protein targeting; essential for viability; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006384]

RHC31

Chromosome XVI: 895,961-897,004 forward strand.

R64-1-1:BK006949.2

This gene has 1 transcript (splice variant), 235 orthologues, 1 paralogue and is a member of 2 Ensembl protein families.

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