Subunit of heterodimeric nuclear SUMO activating enzyme E1 with Uba2p; activates Smt3p (SUMO) before its conjugation to proteins (sumoylation), which may play a role in protein targeting; essential for viability; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006384]
RHC31
Chromosome XVI: 895,961-897,004 forward strand.
R64-1-1:BK006949.2
This gene has 1 transcript (splice variant), 224 orthologues and 7 paralogues.