Saccharomyces cerevisiae (R64-1-1)
Description

Negative regulator of actin nucleation-promoting factor activity; interacts with Las17p, a homolog of human Wiskott-Aldrich Syndrome protein (WASP), via an N-terminal SH3 domain, and along with LSB1 cooperatively inhibits the nucleation of actin filaments; short-lived protein whose levels increase in response to thermal stress; induces the formation of the [PIN+] and [RNQ+] prions when overproduced; PIN3 has a paralog, LSB1, that arose from the whole genome duplication [Source:SGD;Acc:S000006358]

Synonyms

LSB2

Location

Chromosome XVI: 834,565-835,212 forward strand.

R64-1-1:BK006949.2

About this gene

This gene has 1 transcript (splice variant), 322 orthologues, 1 paralogue and is a member of 2 Ensembl protein families.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
PIN3YPR154W_mRNA648215aaYPR154W
 
Protein coding
Q06449 NM_001184251.1
NP_015480.1

Gene-based displays