Essential helicase component of heterohexameric MCM2-7 complexes; MCM2-7 complexes bind pre-replication complexes on DNA and melt DNA prior to replication; forms an Mcm4p-6p-7p subcomplex; shows nuclear accumulation in G1; homolog of S. pombe Cdc21p [Source:SGD;Acc:S000006223]
CDC54, HCD21
Chromosome XVI: 596,750-599,551 forward strand.
R64-1-1:BK006949.2
This gene has 1 transcript (splice variant), 357 orthologues, 5 paralogues and is a member of 1 Ensembl protein family.