2-methylisocitrate lyase of the mitochondrial matrix; functions in the methylcitrate cycle to catalyze the conversion of 2-methylisocitrate to succinate and pyruvate; ICL2 transcription is repressed by glucose and induced by ethanol [Source:SGD;Acc:S000006210]
Chromosome XVI: 567,269-568,996 reverse strand.
R64-1-1:BK006949.2
This gene has 1 transcript (splice variant), 281 orthologues and 3 paralogues.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
ICL2 | YPR006C_mRNA | 1728 | 575aa | YPR006C | Protein coding | Q12031 | - | Ensembl Canonical, |