Iron-sulfer protein required for synthesis of Wybutosine modified tRNA; Wybutosine is a modified guanosine found at the 3'-position adjacent to the anticodon of phenylalanine tRNA which supports reading frame maintenance by stabilizing codon-anticodon interactions; induction by Yap5p in response to iron provides protection from high iron toxicity; overexpression results in increased cellular iron [Source:SGD;Acc:S000006128]

Chromosome XVI: 159,909-162,341 forward strand.

R64-1-1:BK006949.2

This gene has 1 transcript (splice variant) and 242 orthologues.

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