Essential protein involved in regulation of transcription; removes Spt15p (TBP) from DNA via its C-terminal ATPase activity; may have a role in ensuring that soluble TBP is available to bind TATA-less promoters; forms a complex with TBP that binds TATA DNA with high affinity but with altered specificity; the Mot1p-Spt15p-DNA ternary complex contains unbent DNA; coregulates transcription with Spt16p through assembly of preinitiation complex and organization of nucleosomes [Source:SGD;Acc:S000006003]
BTAF1, BUR3, LPF4
Chromosome XVI: 398,480-404,083 reverse strand.
R64-1-1:BK006949.2
This gene has 1 transcript (splice variant), 365 orthologues and 16 paralogues.