Description
Guanine nucleotide exchange factor (GEF); involved in vesicle-mediated vacuolar transport, including Golgi-endosome trafficking and sorting through the multivesicular body (MVB); specifically stimulates the intrinsic guanine nucleotide exchange activity of Rab family members (Vps21p/Ypt52p/Ypt53p); partially redundant with GEF VPS9; required for localization of the CORVET complex to endosomes; contains a VPS9 domain [Source:SGD;Acc:S000005991]
Location
Chromosome XVI: 420,948-422,786 forward strand.
R64-1-1:BK006949.2
About this gene
This gene has 1 transcript (splice variant), 185 orthologues and 1 paralogue.
Transcripts
| Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
|---|---|---|---|---|---|---|---|---|
| MUK1 | YPL070W_mRNA | 1839 | 612aa | YPL070W | Protein coding | Q02866 | - | Ensembl Canonical, |
![[RSS logo]](/i/rss_icon_16.png "Ensembl blog"){kind=icon}
![[twitter logo]](/i/twitter.png "Follow us on Twitter!")
