Saccharomyces cerevisiae (R64-1-1)

Guanine nucleotide exchange factor (GEF); involved in vesicle-mediated vacuolar transport, including Golgi-endosome trafficking and sorting through the multivesicular body (MVB); specifically stimulates the intrinsic guanine nucleotide exchange activity of Rab family members (Vps21p/Ypt52p/Ypt53p); partially redundant with GEF VPS9; required for localization of the CORVET complex to endosomes; contains a VPS9 domain [Source:SGD;Acc:S000005991]


Chromosome XVI: 420,948-422,786 forward strand.


About this gene

This gene has 1 transcript (splice variant), 185 orthologues and 1 paralogue.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
Protein coding
Q02866 -Ensembl Canonical